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For sale online: JWH-018. The synthetic cannabinoid JWH-018 is a component of the home-grown mixture “Zest” in various forms. The euphoric effects of this Spice cannabinoid, which are similar to those of cannabis’ 9-THC, are the main reason for its illegal use. Even though JWH-018 is much stronger than virtually equal amounts of cannabis, it poses a major challenge for the detection of standard 9-THC tests. JWH-018 online kaufen – KONTAKT

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The media have reported at least one case of JWH-018 addiction. The client took JWH-018 day after day over a very long period of time. The negative consequences of withdrawal were more severe than those of cannabis addiction. Beim Online-Verkauf von JWH-018 wurde beobachtet, dass sich die Dicke der CB1-Rezeptoren nach der Einnahme deutlich verändert, so dass eine Desensibilisierung schneller eintritt als bei ähnlichen Cannabinoiden.

The death of a South Carolina high school baseball player was reported on October 15, 2011, by Anderson County Coroner Greg Shore, was attributed to “drug intoxication and organ deprivation” by JWH-018. The city of Anderson S.C. finally delivered on Dec. 16, in response to a FOIA request, an email about the Nov. 4 case.

Compared to THC, which is a partial agonist at the CB1 receptors, JWH-018, many other synthetic cannabinoids and JWH-018 for sale online are full agonists. THC has been shown to impair GABA receptor neurotransmission in the brain through a number of mechanisms. Because it inhibits GABA neurotransmission more effectively than THC, JWH-018 has been implicated as a cause of seizures and convulsions in a small number of cases (mostly in non-standard JWH clients). When used excessively, cannabinoid receptor full agonists can put the user in real danger.

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The negative effects of consuming JWH-018 purchased online have been demonstrated on both a physical and psychological level. In one study, insane relapses and unpleasant side effects were described after inhalation of JWH-018 in patients with mental illness who had received all-round treatment.[21] It has been recommended that individuals with risk factors for mania (e.g. history or family history of psychosis) should avoid the use of JWH-018 and other synthetic cannabinoids due to concerns that they may trigger psychosis in vulnerable individuals.

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